Application of nanotechnology

The world market for products that contain nanomaterials is expected to reach $2.6 trillion by 2015. The use of nanotechnology has stretched across various streams of science, from electronics to medicine. Bioactives are known to prevent aging, cancer, and other diseases for an overall improved health of the consumer. Nanodelivery provides a means to control stability, solubility, and bioavailability, and also increase shelf-life, consumer acceptability, functionality, safety of products, and marketing value. Nanodelivery systems are valuable prospects for nanotechnology in pharmaceutics, cosmetics as well as food industries. Nano-Bioactives are a new class of functional products developed by
nanodelivery systems using natural plant-derived lipids and their derivatives as raw materials. Nanodelivery systems can effectively improve the solubility, stability, biological activity of bioactive substances, also decrease their irritation and odor, and promote transdermal absorbtion, improve bioavailability. Nano-Bioactives can be used in pharmaceutical, food and cosmetics products.
Nanodelivery systems can provide formulators with the ability to carry cosmetic actives(suitable for fat-soluble ingredients, also for water-soluble ingredients)to deeper skin layers, increasing ingredient availability to the skin. In some instances, this greater availability can lead to substantially better ingredient performance, even at lower use levels. As an encapsulated cosmetic active, Nanodelivery delivery system can also enhance the stability of some ingredients by shielding them from common environmental factors. PuriPharma can work with customers to provide customized encapsulated solutions.
Raw materials processed with nanodelivery systems significantly enhance their efficacy and application scope beyond the limitations of traditional formulas.Thus Nano-Bioactives on the one hand helps you to design new pharmaceutical, and cosmetics, food, beverage or supplement products. On the other hand it can optimize your product´s shelf life or manufacturing processing, whenever you encounter limits of raw materials/ingredients due to dissolution problems, pH restrictions or distribution hurdles. Nano-Bioactives has proven its superior benefits in human clinical trials as well as in reliable industry and laboratory studies.
3.1 Application of nanotechnology in dermatology and skin care
Sites in skin for nanoparticle delivery. Topical nanoparticle drug delivery takes place in three major sites: stratum corneum (SC) surface (panel a), furrows(dermatoglyphs) (panel b), and openings of hair follicles (infundibulum) (c). The nanoparticles are shown in green and the drug in red. Other sites for delivery are the viable epidermis (E) and dermis (D).

Follicular pathway of percutaneous uptake of nanoparticles

Kinetics of the storage of nanoparticles in the hair follicles,the nanoparticles were deposited efficiently in the hair follicles where they were stored for at least 10 days

Smaller particles penetrating into deeper layer of the epidermis

The occlusion factor of lipid nanoparticles depends on various factors: at identical lipid content, reducing the particle size leads to an increase in particle number, the film becomes denser (left) and therefore the occlusion factor increases. At a given particle size, increasing the lipid concentration increases particle number and density of the film (right) which also leads to a higher occlusion factor.
3.2 Application of nanotechnology in functional food

Improve the solubility, stability, biological activity of food bioactive, and promote absorbtion.

Enhance oral bioavailability
3.3 Application of nanotechnology in drug delivery